ESTUDIO DEL EFECTO DESTUDIO DEL EFECTO DE LAS VARIABLES DE PROCESO EN LA MORFOLOGÍA DE ANDAMIOS 3D OBTENIDOS POR LA TÉCNICA DE ELECTROSPINNING

Abstract

3D scaffold structures were obtained by electrospinning technique, using a polylactic acid PLA solution. For to study the effect of process parameters on the morphology of scaffold was change: concentrations of the solution, type of collector, the tip-collector gap distance (d) and the voltage applied (V). Subsequently, using Scanning Electron Microscopy (SEM), was study the morphology of the obtained meshes allowing to understand the effect of different parameters in the structures, where d and V were the most crucial and interdependent. Finally was found a optimal concentration that allows a good spraying and sinterization between fibers and a widest range of fiber diameters in micro and nanoscale by changing V or d without obtaining defects, also it was possible to orient the fibers depending on the type of collector.